Fig. 3

a Phase contrast microscopic and b scanning electron microscopic images of HCT 15 cells treated with control, free celecoxib (IC₅₀), liposomal celecoxib (IC₅₀), and empty liposomes (equivalent to volume of liposomal celecoxib) for 48 h. a In phase contrast microscopic images, the apoptotic cells are marked with arrows. All images were taken under the identical instrumental conditions and presented at the same intensity scale. b In SEM images, healthy filopodia and lamellipodia are marked with arrowheads and truncated lamellipodia and filopodia are marked with arrows