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Table 1 Characterization of EILDV-conjugated and non-conjugated micelles

From: EILDV-conjugated, etoposide-loaded biodegradable polymeric micelles directing to tumor metastatic cells overexpressing α4β1 integrin

Formulations code

Particle size (nm)

Polydispersity Index

Zeta potential (mV)

% drug entrapment

% drug loading

% conjugation of EILDV

EPCL235

46.2 ± 4.5

0.176

−8.7 ± 1.9

75.3 ± 3.6

3.39 ± 0.16

85.3 ± 7.4

EPCL570

80.3 ± 4.8

0.198

−9.3 ± 2.2

83.9 ± 4.9

3.77 ± 0.22

89.2 ± 6.3

MPCL235

38.5 ± 2.5

0.152

−4.0 ± 0.4

81.1 ± 2.0

3.90 ± 0.10

MPCL570

73.3 ± 4.0

0.143

−4.6 ± 0.3

92.0 ± 3.4

4.40 ± 0.17

  1. Results are the mean ± SD (n = 3)