Fig. 4

Bar diagram presents the IC₅₀ dose of GNP-NKCT1 (1, 2, and 3) on U937 cell line (a and b) and K562 cell line (c and d), determined by trypan blue exclusion method. On U937 cell after 24 h IC₅₀ dose = 1.5 μg/ml (a) and after 48 h IC₅₀ dose = 1.2 μg/ml (b). On K562 cell after 24 h. IC₅₀ dose = 0.8 μg/ml (c) and after 48 h IC₅₀ dose = 0.75 μg/ml (d). Result of MTT assay on U937 cell line [e (24 h) and f (48 h)] and on K562 cell [g (24 h) and h (48 h)]. Effect of GNP-N KCT1 and imatinib mesylate on normal lymphocyte. Cell count by trypan blue exclusion (4i) and by MTT assays (4j). Each value represents quadruplicate samples of mean ± SEM. *P < 0.05 as compared to control