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Table 4 Model coefficients estimated by multiple regression analysis for PS of exemestane-loaded cPCL NPs

From: Encapsulation of exemestane in polycaprolactone nanoparticles: optimization, characterization, and release kinetics

Factor

Coefficients

t stat

p value

Intercept

207.4

8.7941

0.0031*

X 1

13.0775

1.5684

0.2148

X 2

56.1863

6.7384

0.0067*

X 3

−38.3225

−4.5960

0.0194*

X 1 X 2

−10.0588

−0.8530

0.4563

X 1 X 3

2.3788

0.2017

0.8530

X 2 X 3

25.4188

2.1556

0.0301*

X 1 2

51.0381

3.2718

0.0467*

X 2 2

19.6131

1.2573

0.2976

X 3 2

−12.2444

−0.7849

0.4898

  1. *p < 0.05, significance level