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Table 3 Cell cycle analysis of Ehrlich ascites tumor cells in response to AgNPs treatment and gamma irradiation

From: Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity

Animal groups

subG1 (%)

Go/G1 (%)

S (%)

G2/M (%)

Control

9.9 ± 3.2

7.57 ± 0.9

3.4 ± 0.4

1.2 ± 0.04

AgNPs

68.3 ± 5.2ab

12.5 ± 1.0ab

4.3 ± 0.3ab

1.3 ± 0.05ab

Rad

52.0 ± 3.2ab

12.0 ± 1.6ab

4.0 ± 0.3ab

2.8 ± 0.05a

Eh

32.3 ± 3.4a

19.5 ± 2.9a

5.8 ± 0.3a

3.1 ± 0.04

Eh + AgNPs

81.8 ± 2.8ab

10.3 ± 0.9ab

2.1 ± 0.3ab

1.5 ± 0.03ab

Eh + Rad

71.7 ± 2.6ab

13.97 ± 1.0ab

4.8 ± 0.6ab

2.9 ± 0.05a

Eh + Rad + AgNPs

98.1 ± 3.0ab

0.38 ± 0.1ab

0.0 ± 0.0ab

0.00 ± 0.0ab

  1. aSignificant compared to control group
  2. bSignificant compared to tumor bearing group