Table 4 Various parameters of optimized formulation of PLGA and PLGA-PEG-NH2 NPs
From: Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer
S. No. | Parameters | PLGA nanoparticles | PLGA-PEG-NH2 nanoparticles |
|---|---|---|---|
1 | Size (nm) | 178 ± 8.5 | 132.5 ± 10 |
2 | Polydispersity index (PDI) | 0.095 ± 0.04 | 0.072 ± 0.03 |
3 | Zeta potential (mV) | −59.88 ± 3.5 | −38.43 ± 2.3 |
4 | % Drug entrapment efficiency | 35.16 ± 1.04 | 34.56 ± 1.35 |