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Table 1 Summary of dose enhancement factors (DEF) ± uncertainties for the cell lines investigated when irradiated at 2 Gy, 4 Gy and 8 Gy after treatment with 1.9 nm gold nanoparticles

From: The role of mitochondrial function in gold nanoparticle mediated radiosensitisation

 

MDA-MB-231

DU145

T98G

2 Gy

1.23 ± 0.14

1.01 ± 0.20

1.90 ± 0.22

4 Gy

1.20 ± 0.06

1.06 ± 0.10

1.57 ± 0.08

8 Gy

1.17 ± 0.02

1.1 ± 0.04

1.35 ± 0.03

  1. DEF is defined here as the ratio of doses which lead to equal levels of cell survival with and without GNPs. DEFs can vary with delivered dose, and are quoted with reference to the dose delivered to cells in the absence of GNPs.