Table 1 Dose enhancement effect in terms of DEF, DEF20 % and SER4Gy for Panc1 cells incubated with 0.5 mM AGuIX
From: AGuIX nanoparticles as a promising platform for image-guided radiation therapy
Irradiation | |||||
|---|---|---|---|---|---|
Preparation | 220Â kVp | 6 MV FFF | 6 MV STD | ||
AGuIX no incubation | AGuIX 1h incubation washing | AGuIX 1Â h incubation unwashing | AGuIX 1Â h incubation unwashing | ||
DEF | 1.09 | 1.17 | 1.46 | 1.23 | 1.19 |
DEF 20Â % | 1.01 | 1.1 | 1.31 | 1.3 | 1.23 |
Sensitivity (SER4Gy) | 1.05 | 1.19 | 1.41 | 1.2 | 1.12 |
p value | 0.131 | 0.038 | *** | 0.009 | 0.011 |