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Table 1 Target molecule and common recognizing elements modified on graphene/graphene oxide for detecting cancer cells

From: Electrochemical and optical biosensors for early-stage cancer diagnosis by using graphene and graphene oxide

Targeted molecules

Surface modification and recognizing elements

Disease

References

DNA-t

DNA-C and DNA-r.AuNP

Breast cancer

Rasheed et al. (2014)

Nucleolin

Aptamers, e.g., AS1411

Any type of cancer

Feng et al. (2011)

Anti-CRP antibody

CRP antibody

Lung cancer, colorectal cancer, myeloma cancer, prostate cancer

Zhu (2015)

PCG

PPi

Melanoma cancer

Muthuraj et al. (2017)

Folate receptor

Folate-modified hydrophilic polymers

Epithelial-derived tumors

Li et al. (2016)

Anti-CRP antibody

HRP anti-CRP antibody

Lymphoma cancer

Zhu et al. (2010)

Ab-DNA

Au nanoparticle-tagged DNA

Breast cancer cells

Jung et al. (2010)