Fig. 5
Administration of RALA/pEGFP-N1 nanoparticles to immunocompetent mice does not provoke a neutralizing antibody response. Flow cytometric analysis of GFP in PC3s after incubation of RALA/pEGFP-N1 nanoparticles with sera from C57BL/6 mice that received the indicated treatment (PBS/DNA/RALA/NPs) weekly for up to 3 weeks (a Week 1; b. Week 2; c. Week 3). *p < 0.05, **p < 0.01 compared to expression elicited by RALA/pEGFP-N1 nanoparticles (NP) that had been incubated in sera from mice that had received nanoparticles (multiple comparisons ANOVA)