From: Comb-like PEG-containing polymeric composition as low toxic drug nanocarrier
Number of animals | Dose of PNC, mg/kg of body weight (ml of injected solution) | Dose of PNC, mg/kg of body weight (ml of injected solution) |
---|---|---|
Rats | Mice | |
6 | 57.7 (1.0) | 48.3 (0.1) |
6 | 135 (3.0) | 148.5 (0.3) |
6 | 225 (5.0) | 235.7 (0.5) |
6 | 440 (10.0) | 471.4 (1.0) |
6 (repeat injection) | 440 (10.0) | 471.4 (1.0) |