Fig. 7
From: Nanotechnology approaches to addressing HER2-positive breast cancer
(Originally published by Dove Medical Press Limited)
A schematic illustration of the synthesis of DCLK1–HA–PEG–PLGA NP. DCLK1, doublecortin-like kinase 1; DOX, doxorubicin; EDC, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride; FITC, fluorescein isothiocyanate; HA, hyaluronic acid; NHS, N-hydroxysuccinimide; Ig, immunoglobulin; NP, nanoparticle; PEG, poly(ethylene glycol); PLGA, poly(d,l-lactide-co-glycolide); R6G, rhodamine 6G. Reprinted with permission from A novel double-targeted nondrug delivery system for targeting cancer stem cells Qiao et al. (2016)