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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Nanomedicine-mediated induction of immunogenic cell death and prevention of PD-L1 overexpression for enhanced hepatocellular carcinoma therapy

Fig. 5

NPDOX/siPD-L1 regulated the populations of matured dendritic cells and cytotoxic T cells and cytokine expression patterns in the tumor tissues. ad Flow cytometry was used to analyze CD45+CD11b+CD11c+ DCs and CD8+ cytotoxic T cells. eg The expressions of TGF-β, IL12p70, and IFN-γ in tumor tissues were determined using ELISA. Data were represented as mean ± SD (n = 8). *p < 0.05, **p < 0.01, ***p < 0.001

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