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Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Ultrasound-activated nano-TiO2 loaded with temozolomide paves the way for resection of chemoresistant glioblastoma multiforme

Fig. 2

Effect of ultrasound-activated TiO2 nanosticks with TMZ on glioblastoma (GBM). a Bright-field micrographs showing the anticancer effect of ultrasound-activated TiO2 nanosticks with TMZ on TMZ-resistant GBM cells. The back arrowhead indicated the apoptotic cells’ round morphology after treatment. b MTT assay for cell viability of TMZ-resistant GBM cells after sonication. The viability % is with reference to untreated control. ** shows a highly significant difference between the two groups. c Western blot data showing apoptosis effect of TiO2 nanosticks loaded with TMZ on TMZ-resistant GBM cells after sonication. d Annexin-V PI assay apoptosis data of U251–TMZ resistant cells after treatment with TiO2 nanosticks loaded with TMZ and ultrasound activated. (N = 3)

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Cancer Nanotechnology

ISSN: 1868-6966

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