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Table 1 Composition of the different formulae of N. sativa essential oils used for the evaluation of anticancer activity

From: Cytotoxic, apoptotic, and genetic evaluations of Nigella sativa essential oil nanoemulsion against human hepatocellular carcinoma cell lines

Abbreviation

Definition

Composition

Delivery media

F0

Distilled unformulated essential oil

Volatile oil (1.0%)

DEMSO

F1

Essential oil formulated in nanoemulsion using binary surfactant mixturea

Volatile oil (1.0%)

Surfactant mixturea (2.0%)

PG (0.8%)

Water (96.2%)

Water

F2

Essential oil formulated in nanoemulsion using single surfactantb

Volatile oil % (1.0%)

Surfactantb (2.0%)

PG (0.8%)

Water (96.2%)

Water

  1. PG propylene glycol
  2. aTween 80/Tween 20 (2:1 weight ratio)
  3. bTween 80 only