Fig. 6
Effects of β-CD-CL-Scu-cRGD on proliferation and apoptosis of colon cancer cells (LoVo). LoVo cells were treated with Scu (40 μg/mL) or β-CD-CL-Scu-cRGD (40 μg/mL). A The fluorescence intensity of nanoparticles in LoVo cells by flow cytometry. B IC50 of β-CD-CL-Scu-cRGD, β-CD-CL-cRGD and Scu to LoVo cells. C Cell proliferation was determined by MTT assay. D Cell viability of 24 h and 48 h. E Images of the cell colony assay showing stained colonies resulting from different treatments. F Statistics of cell colony assay. G Images of the cell apoptosis by flow cytometry. H Statistics of cell apoptosis. *p ˂ 0.05, **p ˂ 0.001, ***p and ****p ˂ 0.0001