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Fig. 1 | Cancer Nanotechnology

Fig. 1

From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancer

Fig. 1

The silencing of ABCC9 represses BC malignant phenotypes in vitro and in vivo. A–G The MDA-MB-231 and MDA-MB-468 cells were treated with ABCC9 shRNA. A The presence of ABCC9 was analyzed by qPCR. B, C The cell viability was determined by CCK-8 assays. D The cell proliferation was detected by Edu analysis. E The apoptosis was assessed by flow cytometry analysis. F The expression of caspase3, cleaved caspase3, caspase9, and cleaved caspase9 was detected by Western blot analysis. G The cell invasion/migration was examined by transwell analysis. H, I The nude mice were injected with MDA-MB-231 cells treated with ABCC9 shRNA. The tumor growth of MDA-MB-231 cells was detected in the xenograft model. **P < 0.01

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Cancer Nanotechnology

ISSN: 1868-6966

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