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Fig. 3 | Cancer Nanotechnology

Fig. 3

From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancer

Fig. 3

The silencing of ABCC9 attenuates Dox resistance of BC cells. A The expression of ABCC9 was detected by qPCR in MDA-MB-231 and MDA-MB-468 cells and MDA-MB-231/Dox and MDA-MB-468/Dox cells. B–E The MDA-MB-231/Dox and MDA-MB-468/Dox cells were treated with ABCC9 shRNA. B, C The IC50 value of Dox was analyzed by CCK-8 assays. D The cell proliferation was detected by Edu analysis. E The apoptosis was assessed by flow cytometry analysis. F The expression of caspase3, cleaved caspase3, caspase9, and cleaved caspase9 was detected by Western blot analysis. **P < 0.01

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Cancer Nanotechnology

ISSN: 1868-6966

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