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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancer

Fig. 4

ZON attenuates Dox resistance of BC cells. A–D The MDA-MB-231/Dox and MDA-MB-468/Dox cells were treated with ZON. A The IC50 value of Dox was analyzed by CCK-8 assays. B The cell proliferation was detected by Edu analysis. C The apoptosis was assessed by flow cytometry analysis. D The expression of p21, BAX, and the total expression and nucleus expression of p53 was measured by Western blot analysis. **P < 0.01

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