Fig. 4From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancerZON attenuates Dox resistance of BC cells. A–D The MDA-MB-231/Dox and MDA-MB-468/Dox cells were treated with ZON. A The IC50 value of Dox was analyzed by CCK-8 assays. B The cell proliferation was detected by Edu analysis. C The apoptosis was assessed by flow cytometry analysis. D The expression of p21, BAX, and the total expression and nucleus expression of p53 was measured by Western blot analysis. **P < 0.01Back to article page