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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancer

Fig. 5

ZON induces ferroptosis of BC cells by targeting p53. A, B The MDA-MB-231/Dox and MDA-MB-468/Dox cells were treated with erastin and ZON. The cell viability was determined by CCK-8 assays. C–F The MDA-MB-231/Dox and MDA-MB-468/Dox cells were treated with erastin, p53 shRNA, and ZON. The levels of GSH (C), MDA (D), lipid ROS (E), and iron (F) were detected. **P < 0.01

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