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Fig. 3 | Cancer Nanotechnology

Fig. 3

From: Baicalin-loaded folic acid-modified albumin nanoparticles (FA-BSANPs/BA) induce autophagy in MCF-7 cells via ROS-mediated p38 MAPK and Akt/mTOR pathway

Fig. 3

FA-BSANPs/BA inhibited proliferation of MCF-7 cells. A Evaluation of cell viability. B Distribution of cell cycle. C Morphological changes in apoptotic nuclei. Red arrows indicate chromatin condensation and nuclear fragmentation. Scale bars = 20 µm. D Apoptosis detected by flow cytometry using annexin V-FITC/PI staining. E Apoptotic rate. F Expression of apoptosis and cell cycle related proteins detected by western blot. Results are shown as mean ± SD (n = 3), *p < 0.05, **p < 0.01, ***p < 0.001

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