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Table 1 Physicochemical properties of SAHNs. The data are expressed as the mean ± standard deviation (SD, n = 3). Characterization of SAHNs by molecular weight of HA

From: Hyaluronan self-agglomerating nanoparticles for non-small cell lung cancer targeting

Volume of 0.05 M

Fe3+ ion (µL)

v/v (%)

800,000 Da

950,000 Da

1,500,000 Da

3,600,000 Da

150

0.0099

139 nm

130 nm

163 nm

N.D

200

0.0132

112 nm

108 nm

140 nm

N.D

250

0.0164

109 nm

120 nm

164 nm

95.2 nm

300

0.0196

125 nm

137 nm

151 nm

102 nm

350

0.0228

233 nm

282 nm

144 nm

117 nm

  1. *N.D not detected: the results did not meet the criteria
  2. Data are expressed as mean ± standard deviation (SD, n = 3)
  3. A comparative study of molecular weight selection according to HA was performed at a concentration of 0.1% HA