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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Multifunctional nanocomposites DDMplusAF inhibit the proliferation and enhance the radiotherapy of breast cancer cells via modulating tumor-promoting factors and metabolic reprogramming

Fig. 6

Detection of apoptosis in DDMPlusAF and/or 6 Gy treated BCCs. Representative dot-plot images of the Annexin-V-FITC and PI performed on BCCs treated with DDMPlusAF and/or 6 Gy. a DDMPlusAF and 6 Gy induced apoptosis and necrosis in MCF-7 cells, and b DDMPlusAF and 6 Gy induced apoptosis and necrosis in MDA-MB-231 cells. The overall percentage of dead cells comprises the total apoptotic cells (early and late) as well as the necrotic cells. Data are represented as mean ± SEM, a1p < 0.001, a2p < 0.01, a3p < 0.05 vs. Control group; b1p < 0.001, b2p < 0.01, b3p < 0.05 vs. DDMPlusAF group; c1p < 0.001, c2p < 0.01, c3p < 0.05 vs. 6 Gy group. Control group is MCF-7 or MDA cells

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Cancer Nanotechnology

ISSN: 1868-6966

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