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Fig. 7 | Cancer Nanotechnology

Fig. 7

From: Multifunctional nanocomposites DDMplusAF inhibit the proliferation and enhance the radiotherapy of breast cancer cells via modulating tumor-promoting factors and metabolic reprogramming

Fig. 7

Modulatory effect of DDMPlusAF and/or 6 Gy on the biochemical mediators constitute TPF in BCCs. a HIF-1α, b TNF-α, c p53, d PPAR-α, e IL-10, and f PRMT-1. All group values are represented as mean ± SEM. a1p < 0.001, a2p < 0.01, a3p < 0.05 vs. control; b1p < 0.001, b2p < 0.01, b3p < 0.05 vs. DDMPlusAF group; c1p < 0.001, c3p < 0.05 vs. 6 Gy group. Blue columns denote MCF-7 cells and red columns stand for MDA-MB-231 cells

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