Antiproliferation effects of nanophytosome-loaded phenolic compounds from fruit of Juniperus polycarpos against breast cancer in mice model: synthesis, characterization and therapeutic effects

Table 6 The results of liver enzymes analysis and lipid peroxidation in the liver tissue of TUBO tumor-bearing mice during experiment receiving different treatments

Parameters	T1	T2	T3	T4	SEM
ALT (IU/L)	177^a	145^b	123^c	125^c	8.72
AST (IU/L)	63^a	50^b	46^b	52^b	4.18
ALP (IU/L)	789^a	466^b	312^c	455^b	51.7
MDA^* (%)	100.0^a	92.4^b	84.7^c	94.6^b	2.47

Control (T1); mice receiving HPF (50 mg TPC/Kg/BW) (T2); mice were receiving nanophytosome-loaded HPF (50 mg TPC/Kg/BW) (T3); and mice receiving tamoxifen (0.4 mg/kg/BW similar dose to the clinical dose in humans) as an antiproliferative drug (T4). Different letters (a, b, c, d) in the same row represent significant difference (p < 0.05). The analysis was performed in triplicates

ISSN: 1868-6966