Table 1 Effects of Tween-80:Tween-60:cholesterol:DOTAP:PEG ratios on the EE%, PDI, R%, diameter size (nm), and Zeta potential (mV) of the Cur-loaded system
Code | Tween-80 | Tween-60 | Cholesterol | DOTAP% | PEG% | EE% | PDI | Zeta (mv) | Diameter (nm) | R% (24 h, 37 °C) |
|---|---|---|---|---|---|---|---|---|---|---|
F1 | 90 | 0 | 10 | – | – | 30.43 | 0.24 ± 0.003 | − 25 ± 0.02 | 120 ± 0.03 | 8 ± 0.23 |
F2 | 0 | 90 | 10 | – | – | 50.14 | 0.27 ± 0.24 | − 24 ± 0.15 | 117 ± 0.98 | 15 ± 0.23 |
F3 | 75 | 15 | 10 | – | – | 78.34 | 0.21 ± 0.16 | − 24 ± 0.34 | 110 ± 0.45 | 19 ± 0.67 |
F4 | 70 | 15 | 10 | – | 5 | 85.34 | 0.19 ± 0.48 | − 25 ± 0.67 | 101 ± 0.56 | 21 ± 0.78 |
F5 | 70 | 15 | 10 | 5 | – | 90.66 | 0.17 ± 0.19 |  + 5 ± 0.45 | 93 ± 0.34 | 28 ± 0.56 |
F6.1 | 65 | 12.5 | 7.5 | 10 | 5 | 99.85 | 0.15 ± 0.067 |  + 16 ± 0.67 | 86 ± 0.67 | 33 ± 0.48 |