Fig 12.
A Sketch of AuNPs hybridization with antimonene nanosheet assisted SPR biosensor for determining miRNA. I The antimonene nanosheets was assembled on the gold film. II AuNPs–ssDNA adsorbed on the antimonene nanosheet. III Tested sample of miRNA flowed over the antimonene monolayer surface and paired up to form a double-strand with complementary AuNPs–ssDNA. IV Interaction between miRNA and ssDNA led to the release of AuNPs–ssDNA from the nanosheet. B AFM images of antimonene on Au film (scale bar = 2 μm). C SPR spectrum with miRNA concentrations ranging from 10−17 to 10−11 M. D Relationship between the SPR angle and miRNA concentration. Reprinted with permission from ref. (Xue et al. 2019).