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Fig. 8 | Cancer Nanotechnology

Fig. 8

From: Carbon nanoparticles induce DNA repair and PARP inhibitor resistance associated with nanozyme activity in cancer cells

Fig. 8

CNPs mediated cell death is reversed by PARP inhibition and can be overcome by phosphatase inhibition to induce synthetic lethality. a CNPs resistant to PARP inhibition by olaparib at low dose and combined treatment by PPi. b CNPs resistant to PARP inhibition by olaparib at low dose but not in high dose. c Beet CNPs distribution in HELA cells. d The comparison of the FT-IR spectra for beet CNPs and the combination with PARPi (Olaparib)

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Cancer Nanotechnology

ISSN: 1868-6966

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