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Table 2 Ponatinib IC50 value

From: Tyrosine kinase inhibitor-loaded biomimetic nanoparticles as a treatment for osteosarcoma

 

577

F420

RF379

TCCC-OS94

TCCC-OS202

Pon (µM)

3

1.2

0.15

3.8

1.67

Lipo_Pon (µM)

1.1

0.3

0.05

2.87

0.88

Leuko_Pon (µM)

1.45

0.6

0.06

1.70

0.86

  1. Cytotoxicity (IC50 values, µM) following 72-h exposure to Pon, Lipo and Leuko Pon-loaded NPs in a panel of murine OS (577, F420, RF379) and human PDX-derived OS (TCCC-OS94, TCCC-OS202) cell lines