Fig. 5
From: SN38-loaded nanomedicine mediates chemo-radiotherapy against CD44-expressing cancer growth
A Distribution of SH NPs and SH/HA NPs in the main organs and HT29 tumors at 3 and 24 h. B Schematic diagram of the treatment of HT29 tumor-bearing mice. C Relative primary tumor volumes, D representative primary tumor images, and E primary tumor weight, and F body weights of nude mice treated with saline, CPT-11, SH NPs, and SH/HA NPs with or without γ-ray irradiation (6 Gy) (n = 5). G H&E stained images of the heart, liver, spleen, lung, and kidney in mice after treatment with saline, SH NPs, and SH/HA NPs plus 6 Gy of γ-ray at 28 days. Scale bar = 200 µm. *p < 0.05