Polyethylenimine-CO2 adduct templated CaCO3 nanoparticles as anticancer drug carrier

Cancer Nanotechnology

Table 1 Composition of as-synthesized CaCO₃ nanoparticles

Sample	Weight loss by TG (wt%)			Residue^a (wt%)	CaCO₃^b (wt%)	DOX loading (wt%)
Sample	CO₂ (PEI-CO₂)	Organic substance	CO₂ (CaCO₃)	Residue^a (wt%)	CaCO₃^b (wt%)	DOX loading (wt%)
PEI-CO₂@CaCO₃	6.42	12.72	33.94	46.92	77.19
-PEG	3.00	14.95	34.18	47.87	77.73
-FA	5.65	12.99	32.11	49.25	73.03
-PEG-FA^a	3.92	17.64	30.53	47.93	69.39
Durg-loaded
PEI-CO₂@CaCO₃	5.78	18.73	32.16	43.33	73.14	5.91
-FA	6.98	27.14	26.62	39.00	60.54	6.55
-PEG-FA	7.82	31.79	25.36	35.03	57.68	5.79

^aThe residue was obtained at the final temperature (bare particles: 795 °C; drug-loaded particles: 765 °C)
^bThe CaCO₃ content was calculated from the third weight loss (i.e., CO₂ content from CaCO₃)

ISSN: 1868-6966