Skip to main content

Table 3 Tumor growth inhibition and survival time data of CT-26 colon-bearing BALB/c mice (n = 6) after different treatment modalities

From: Targeted magnetochemotherapy modified by 5-Fu-loaded thermally on/off switching nanoheaters for the eradication of CT26 murine colon cancer by inducing apoptotic and autophagic cell death

Treatment groups

Tumor growth inhibition

Median tumor volume (mm3)

Mean growth Inhibition rate (%)*

P-value

Saline

2845.7

–

–

MNPs-Fa

2795.5

1.76

NS

5-Fu

2143.09

24.69

NS

5-Fu/MNPs-Fa

1366.41

51.98

 < 0.01

AMF

1987.65

30.15

NS

AMF + MNPs-Fa

648.42

77.21

 < 0.001

AMF + 5-Fu/MNPs-Fa

198.38

93.02

 < 0.001

  1. *Mean growth inhibition rate (%) was calculated as [(C-T)/C] × 100, where T is mean median tumor volume of treated mice and C is median tumor volume of control mice. NS = not significant
Back to article page

Cancer Nanotechnology

ISSN: 1868-6966

Contact us