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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Carboxylated graphene quantum dots-mediated photothermal therapy enhances drug-membrane permeability, ROS production, and the immune system recruitment on 3D glioblastoma models

Fig. 6

Penetration of DOX after GQDs-mediated PTT. A Representative confocal microscopy images showing spheroid cells labeled with calcein (left) and treated with DOX (red). Scale bar 200 μm. d = penetration depth. B Penetration depth of DOX within spheroids. Data are normalized by penetration depth of DOX. C Fluorescence intensity of DOX inside spheroids. Data are normalized fluorescence intensity of DOX alone. ***p < 0.01 one-way ANOVA and Tukey post-hoc test

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