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Fig. 3 | Cancer Nanotechnology

Fig. 3

From: Doxorubicin-loaded liposomes surface engineered with the matrix metalloproteinase-2 cleavable polyethylene glycol conjugate for cancer therapy

Fig. 3

Cellular interaction (A, B) at 2–8 °C and cell uptake (C, D) at 37 °C of the free Dox and Dox-loaded liposomal formulations in C26 tumor cells. Untreated cells were applied as the control group. Results were assessed by flow cytometry and expressed as MFI. The results are shown as means ± SD (n = 3 independent experiments). Statistical significance is compared to the Caelyx® and designated as follows: ****P < 0.0001. The test was performed in triplicate

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