Table 3 Antitumor effects of the free Dox and Dox-loaded liposomal formulations
Formulation | Time to reach the end point (days) | Tumor growth delay (TGD%) | Median survival time (days) | Percentage increased life span (ILS%) |
|---|---|---|---|---|
PBS | 34.1 ± 2.7 | – | 33.4 | – |
Dox | 41.0 ± 2.7 | 20.96 | 42.7 | 27.76 |
Caelyx® | 53.9 ± 2.1 | 58.19 | 54.0 | 61.72 |
F4 | 42.6 ± 3.1 | 24.95 | 42.8 | 28.18 |
F5 | 65.2 ± 3.7 | 91.48 | 65.7 | 96.76 |
F6 | 57.3 ± 5.8 | 68.23 | 59.8 | 79.12 |