Group | 0 day | 2 days | 4 days | 6 days | 8 days | 10 days | 12 days | 14 days |
---|---|---|---|---|---|---|---|---|
PBS | 87.10 ± 12.2 | 107.9 ± 7.83 | 158.7 ± 9.69 | 208.1 ± 14.8 | 302.0 ± 32.0 | 340.2 ± 48.7 | 406.8 ± 56.2 | 496.7 ± 45.9 |
DOX | 92.2 ± 5.27 | 103.0 ± 4.92 | 121.1 ± 15.4 | 144.0 ± 21.7 | 194.1 ± 23.0 | 223.4 ± 23.8 | 237.8 ± 24.3 | 264.8 ± 23.7 |
DOX + US | 89.0 ± 8.27 | 103.9 ± 10.9 | 114.9 ± 12.6 | 132.6 ± 13.7 | 153.7 ± 13.4 | 196.7 ± 29.7 | 230.4 ± 35.9 | 250.7 ± 48.5 |
O-CS-DOX NDs | 86.9 ± 6.08 | 101.4 ± 9.18 | 133.0 ± 4.80 | 176.8 ± 30.6 | 200.9 ± 41.5 | 247.9 ± 18.8 | 312.0 ± 90.7 | 349.8 ± 79.5 |
O-CS-DOX NDs + US | 86.1 ± 5.02 | 100 ± 3.73 | 123.3 ± 11.3 | 147.9 ± 29.7 | 160.2 ± 34.6 | 198.4 ± 68.9 | 209.8 ± 67.4 | 224.7 ± 65.3 |
CS-DOX NDs + US | 86.8 ± 6.08 | 99.5 ± 3.03 | 118.0 ± 10.8 | 147.9 ± 9.97 | 174.8 ± 26.5 | 211.0 ± 6.34 | 230.7 ± 11.7 | 260.2 ± 28.4 |