Group | 0 day | 2 days | 4 days | 6 days | 8 days | 10 days | 12 days | 14 days |
---|---|---|---|---|---|---|---|---|
PBS | 19.48 ± 3.14 | 19.19 ± 2.64 | 19.11 ± 2.66 | 18.40 ± 2.35 | 18.56 ± 2.37 | 18.06 ± 2.33 | 17.85 ± 2.62 | 17.74 ± 2.65 |
DOX | 16.78 ± 2.33 | 16.60 ± 2.43 | 16.40 ± 2.40 | 16.12 ± 2.57 | 16.14 ± 3.01 | 15.50 ± 2.78 | 14.33 ± 3.38 | 13.53 ± 3.17 |
DOX + US | 18.51 ± 2.76 | 18.21 ± 2.73 | 17.99 ± 2.84 | 17.85 ± 2.94 | 17.58 ± 3.30 | 16.38 ± 2.52 | 15.01 ± 2.68 | 14.17 ± 3.10 |
O-CS-DOX NDs | 18.28 ± 2.09 | 18.05 ± 2.08 | 18.00 ± 2.21 | 17.68 ± 2.15 | 17.95 ± 2.79 | 17.50 ± 2.54 | 16.76 ± 3.15 | 16.22 ± 3.22 |
O-CS-DOX NDs + US | 17.17 ± 3.52 | 16.85 ± 4.04 | 16.75 ± 3.92 | 16.32 ± 3.83 | 15.82 ± 3.72 | 15.51 ± 3.66 | 14.98 ± 3.44 | 14.65 ± 3.52 |
CS-DOX NDs + US | 16.98 ± 2.24 | 16.57 ± 2.08 | 16.72 ± 2.34 | 16.22 ± 2.12 | 15.69 ± 1.6 | 15.34 ± 1.85 | 14.77 ± 1.35 | 13.93 ± 1.53 |