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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Doxorubicin-loaded polymeric nanoparticles containing ketoester-based block and cholesterol moiety as specific vehicles to fight estrogen-dependent breast cancer

Fig. 6

Cytotoxic effect of the empty and DOX-loaded polymeric nanoparticles against estrogen-dependent and estrogen-independent breast cancer cells. Viability of estrogen-dependent (A) and estrogen-independent (C) breast cancer cells in the presence of empty and DOX-loaded polymeric nanoparticles containing DOX as well as free DOX (B and D). Statistical significance for the polymeric nanoparticles without or with DOX or DOX in free form vs. control was marked with (*); comparison of DOX (0.5 µM) at free vs encapsulated form PNP-DOX marked with (^) comparison of PNP vs PNP-DOX marked with (&), concentrations dependent response for PNP-DOX marked with (#), p ≤ 0.05. The data presented constitute average results from three measurements ± SD

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