Table 3 24 h incubation half inhibitory effect (IC₅₀) of the free and nano-RX regimens and their cytotoxic and IC₅₀ fold changes

IC₅₀, µM

Caco-2 cells

64.07

56.31

61.06

25.45

HCT 116 cells

86.79

45.59

54.10

40.22

WI-38 cells

76.30

ND

ND

ND

Cytotoxic fold

Caco-2 cells

Ref.

1.14

1.05

2.52

HCT 116 cells

Ref.

1.90

1.60

2.16

WI-38 cells

Ref.

0.76

0.76

0.76

IC₅₀ fold

Caco-2 cells

Ref.

0.88

0.95

0.40

HCT 116 cells

Ref.

0.53

0.62

0.46

WI-38 cells

Ref.

ND

ND

ND