Fig. 6

In vivo therapeutic efficacy of Man-NPs. a A schematic illustration of the treatment schedule. b The tumor growth curve in K7 subcutaneous tumor-bearing mice following drug treatment (n = 6). (c–h) Individual tumor growth curves in different groups (n = 6). Tumor weight (i), tumor growth inhibition ratio (j) and survival curve (k) after drug treatment (n = 6). l Immunohistochemical staining (brown color) of Ki-67 (scale bar: 50 µm). The right panel displayed the percentage of Ki67 positive results. Comparisons were made using one-way ANOVA with Tukey’s test; ns: no significant difference, *p < 0.05, **p < 0.01, ***p < 0.001