Fig. 4
In vitro phototherapy with OMV-IR780. a, b Thermal images and temperature change curves of OMV-IR780 and OMV upon exposure to a 780 nm CW laser (1 W/cm2). c Relative viabilities of 4T1 cells after treatment with PBS, OMV (~ 20 μg), IR780 (1.6 μg/mL) or OMV-IR780 complex (~ 20 μg) with or without 780 nm CW laser irradiation at 1 W/cm2 for 5 min. d Relative viabilities of 4T1 cells after treatment with OMV-IR780 at different concentrations with 780 nm CW laser irradiation at 1 W/cm2 for 5 min. e Fluorescence images of live/dead staining of 4T1 cells after different treatments. Red color: dead cells; green color: live cells. Scale bar, 100 μm. f Fluorescence images of ROS generation in 4T1 cells after different treatments. Scale bar, 100 μm