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Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Neutrophil membrane-derived nanoparticle loading TLR7 agonists augments radiotherapy efficacy and boosts abscopal effect via regulating tumor microenvironment

Fig. 2

In vitro cell uptake and cytotoxicity of R837@PLGA@Neu in CRC cell lines. A Confocal images of cell uptake of DyLight594 (red) labeled R837@PLGA or R837@PLGA@Neu in CT26 cells (scale bar: 50 nm). Blue represents DAPI staining of the cell nucleus. B Images of cell uptake of DyLight594 (red) labeled R837@PLGA or R837@PLGA@Neu in 3D spheroids of CT26 cells (scale bar: 100 μm). C Cell viability of CT26 cells treated with R837@PLGA or R837@PLGA@Neu for 0, 24, 48, and 72 h. D Cell viability of CRC cells treated with R837@PLGA or R837@PLGA@Neu for 72 h. E Representative flow cytometric plots of cell apoptosis after treatment with R837@PLGA or R837@PLGA@Neu. All numerical data are presented as the mean ± SD

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