Table 5 Stability of CTX-HSA-NPs
Time | Particle size (nm) | PDI | 5% particle < (nm) | 90% particle < (nm) | 99% particle < (nm) |
|---|---|---|---|---|---|
0 h | 108.8 ± 0.9 | 0.072 ± 0.009 | 68.4 ± 1.8 | 150.5 ± 3.5 | 198.0 ± 7.6 |
2 h | 111.2 ± 4.8 | 0.085 ± 0.012 | 67.2 ± 4.1 | 157.7 ± 7.1 | 212.3 ± 12.0 |
4 h | 102.6 ± 2.7 | 0.038 ± 0.054 | 79.0 ± 16.4 | 126.2 ± 24.8 | 152.6 ± 53.4 |
8 h | 107.7 ± 2.4 | 0.080 ± 0.028 | 66.4 ± 7.0 | 150.9 ± 5.3 | 201.4 ± 16.8 |
24 h | 111.3 ± 2.4 | 0.055 ± 0.032 | 75.3 ± 8.7 | 147.3 ± 11.0 | 187.2 ± 26.3 |
48 h | 111.3 ± 3.1 | 0.120 ± 0.054 | 61.5 ± 7.0 | 167.4 ± 18.9 | 238.3 ± 45.6 |
8 days | 112.6 ± 4.6 | 0.125 ± 0.036 | 60.7 ± 4.4 | 171.3 ± 14.9 | 245.9 ± 33.5 |
15 days | 118.0 ± 8.6 | 0.161 ± 0.036 | 58.5 ± 9.2 | 188.4 ± 6.8 | 282.3 ± 13.1 |
24 days | 121.7 ± 0.9 | 0.156 ± 0.041 | 60.9 ± 5.8 | 193.5 ± 10.6 | 288.7 ± 30.5 |
30 days | 221.1 ± 63.0 | 0.676 ± 0.197 | 51.4 ± 20.2 | 525.8 ± 138.8 | 1120.8 ± 307.8 |