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Table 6 LD50 of CTX-Tween

From: Cabazitaxel-loaded human serum albumin nanoparticles combined with TGFβ-1 siRNA lipid nanoparticles for the treatment of paclitaxel-resistant non-small cell lung cancer

Groups

Doses (mg/kg)

n

Dead animals

Mortality (%)

1

51.16

10

0

0

2

56.21

10

0

0

3

61.76

10

4

40

4

67.85

10

4

40

5

74.55

10

7

70

6

81.91

10

8

80

  1. Regression equation: y = − 13.0899 + 9.8838(r = 0.9439)