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Table 7 LD50 of CTX-HSA-NPs

From: Cabazitaxel-loaded human serum albumin nanoparticles combined with TGFβ-1 siRNA lipid nanoparticles for the treatment of paclitaxel-resistant non-small cell lung cancer

Groups

Doses (mg/kg)

n

Dead animals

Mortality (%)

7

122.50

10

0

0

8

137.03

10

0

0

9

153.28

10

1

10

10

171.46

10

2

20

11

191.8

10

5

50

12

214.55

10

8

80

  1. Regression equation: y = − 28.7235 + 14.7901x (r = 0.9909)