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Table 6 ANOVA for the 23 factorial design of PTS-loaded ENs

From: Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations

Response

Source

Sum of Squares

df

Mean Square

F-Value

P-value

EE% (Y1)

Model

21.03

3

7.01

16.82

0.0099

X1

4.68

1

4.68

11.24

0.0285

X2

3.65

1

3.65

8.75

0.0417

X3

12.70

1

12.70

30.48

0.0053

Q24h (Y2)

Model

650.86

6

108.48

13,193.90

0.0067

X1

24.62

1

24.62

2994.45

0.0116

X2

337.15

1

337.15

41,006.66

0.0031

X3

6.65

1

6.65

809.09

0.0224

  1. Values of p < 0.05 indicate that the model is significant, X1: the amount of span 60, X2: the amount of ethanol, X3: the amount of CHO
  2. EE, entrapment efficiency; Q24h, % PTS released after 24 h; df, degree of freedom
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Cancer Nanotechnology

ISSN: 1868-6966

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