Fig. 5

A Schematic view of the treatment process of mice with triple-negative breast cancer cells. B Gemcitabine (Gem) concentration in blood in Gem and platinumCobalt@Gem-hyaluronic acid (HA)-poly[ethylane glycol] (PtCo@Gem-HA-PEG) groups. C Comparison of liver factors include of Alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and D kidney factors include of blood urea nitrogen (BUN) and creatinine (CRA) in control, Gem, PtCo@Gem-HA-PEG with and without photodynamic therapy (PDT) groups. E Weight of mice during 35-day treatment. F Tumor growth inhibition curve in each group after different treatments. G Tumor weight and H its digital photographs recorded from each group. I Histological observation of treated tumor tissues visualized using H&E staining (Scale bars are 100 μm.). Different letters a, b and c are significantly different at P < 0.05. ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001 indicate significant differences