Fig. 6

A Gemcitabine (Gem) and B platinum–cobalt nanozyme concentrations in tumor, liver, spleen, lung, kidney, heart and brain tissues in the Gem and platinumCobalt@Gem-hyaluronic acid (HA)-poly[ethylene glycol] (PtCo@Gem-HA-PEG) groups. C Histological investigations through H&E staining of main organs include of brain, kidney, liver, spleen, lung and heart after 35 days of treatment with Gem and PtCo@Gem-HA-PEG NZ with and without PDT. Scale bars are 100 μm. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 and ^****P < 0.0001 indicate significant differences (ns: non-significant)