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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: An electrostatically conjugated-functional MNK1 aptamer reverts the intrinsic antitumor effect of polyethyleneimine-coated iron oxide nanoparticles in vivo in a human triple-negative cancer xenograft

Fig. 5

Immunohistochemical analysis of the tumor tissues. a Blood vessel density was determined by CD31 staining of snap frozen MDA-MB-231 tumors from the animals treated with the different formulations (Top) and quantified as shown in the graph (Bottom). b Tumor-infiltrating macrophages were determined by F4/80 staining of snap frozen MDA-MB-231 tumors from animals treated with the different formulations (Top) and quantified as shown in the graph (Bottom): two-tailed Mann–Whitney test, *p < 0.05, **p < 0.01, ***p < 0.001. ‘#’ indicates differences between the two groups at each edge of the line; ‘*’ indicates differences between saline group and the indicated one

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Cancer Nanotechnology

ISSN: 1868-6966

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