Fig. 5
From: Advances in blood–brain barrier-crossing nanomedicine for anti-glioma
Adapted from Ref. (Shi et al. 2020) with permission from Dove Medical Press copyright 2020; adapted from ref. (Arcella et al. 2018) with permission from the American Chemical Society copyright 2018
Nanocarrier strategy enhances chemotherapy in glioma. a The TMZ-A2PEC/siPLK1 drug formation and delivery system (Shi et al. 2020). b Design liposomes employing plasma proteins most likely to bind blood–brain barrier receptors to exploit the biomolecular corona (BC) in targeted brain drug delivery (Arcella et al. 2018).